General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).

An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Packaging

25, 100 g in Glass bottle

1 kg in Glass bottle

Warning

Toxicity: Harmful (C)

aggregation number	4 - 10, 3-12
assay	≥96% (TLC)
cation traces	heavy metals: ≤20.0 ppm
CMC	2-6 mM (20-25°C), 4 - 8 mM
color	white to off-white
form	powder
HLB	16
InChI key	FHHPUSMSKHSNKW-SMOYURAASA-M
InChI	1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
manufacturer/tradename	Calbiochem^®
mol wt	micellar wt 1700-4200, micellar avg mol wt 1200-5000
pKa	6.2
Quality Level	100
shipped in	ambient
SMILES string	[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
solubility	H₂O: 2%, clear, colorless
storage condition	desiccated (hygroscopic), OK to freeze
storage temp.	15-25°C